Ribosomal protein S10



Ribosomal protein S10 (RPS10) is one of the 22 proteins which belong to the small subunit of the bacterial ribosome. It functions in binding tRNA to the ribosome and operates as a transcriptional elongation factor. The images at the left and at the right correspond to one representative RPS10, i.e. the crystal structure of Ribosomal protein S10 from Thermus thermophilus (2zm6, chain J).

3D Structures of Ribosomal protein S10
Update June 2011

S10 + Protein
3imq, 3d3b, 3d3c - EcRPS10 +NUSB - Escherichia coli

S10 in small ribosomal subunit
2zm6, 1n36, 1j5e, 3oto - TtRPS10 in 30S ribosomal subunit+THX+16S RRNA – Thermus thermophilus

2vqe, 2vqf, 2uuc, 2e5l, 2uu9, 2uua, 2uub, 3pyn, 3pyq,  3pys,  3pyu - TtRPS10 in 30S ribosomal subunit+16S RRNA+RNA fragment

3kc4 – EcRPS10 in 30S ribosomal subunit

3i1m, 3i1o, 3df1, 3df3, 2vho, 2vhp, 2avy, 2aw7, 1pnx, 3or9, 3ora - EcRPS10 in 30S ribosomal subunit+16S RRNA

1i94, 1fka - TtRPS10 in 30S ribosomal subunit+16S RRNA

1p87, 1p6g - EcRPS10 in 30S ribosomal subunit+16S RRNA – Cryo-EM

3bbn - RPS10 in 30S ribosomal subunit+16S RRNA – Cryo-EM – spinach

S10 in small + large ribosomal subunit
1ml5 - EcRPS10 in 30S ribosomal subunit+50S ribosomal subunit+THX+chain release factor 2+P-site tRNA+tRNA Phe+mRNA fragment+23S RRNA+5S RRNA+16S RRNA - EM

S10 in small ribosomal subunit+ chain release factor
3mr8, 3ms0 – TtRPS10 in 30S ribosomal subunit+THX+chain release factor 1+P-site tRNA+mRNA+16S RRNA

3d5a, 3d5c - TtRPS10 in 30S ribosomal subunit+THX+chain release factor 1+P-site tRNA+E-site tRNA+mRNA +16S RRNA

2b64 - TtRPS10 in 30S ribosomal subunit+THX+P-site tRNA Phe+E-site tRNA Phe+mRNA +16S RRNA+chain release factor 1

2b9m - TtRPS10 in 30S ribosomal subunit+THX+P-site tRNA Phe+E-site tRNA Phe+mRNA +16S RRNA+chain release factor 2

2x9r, 2x9t, 2wh1, 2wh3 - TtRPS10 in 30S ribosomal subunit+THX+chain release factor 2+P-site tRNA+mRNA +16S RRNA

3f1e, 3f1g - TtRPS10 in 30S ribosomal subunit+THX+chain release factor 2+P-site tRNA+E-site tRNA +16S RRNA

S10 in small ribosomal subunit+tRNA+mRNA
2hgi - TtRPS10 in 30S ribosomal subunit+16S RRNA+tRNA Phe+tRNA fMet

2hgp - TtRPS10 in 30S ribosomal subunit+16S RRNA+tRNA Phe+mRNA

2i2p, 2i2u - EcRPS10 in 30S ribosomal subunit+16S RRNA+tRNA Phe+mRNA

2hgr - TtRPS10 in 30S ribosomal subunit+16S RRNA+tRNA Phe+tRNA fMet+mRNA

1yl4 – TtRPS10 in 30S ribosomal subunit+ tRNA Phe+16S RRNA+THRS mRNA operator

1pns - EcRPS10 in 30S ribosomal subunit+ tRNA Phe+16S RRNA+mRNA

1xnq, 1xnr - TtRPS10 in 30S ribosomal subunit+THX+mRNA+tRNA anticodon+16S RRNA

S10 in small ribosomal subunit+A-site tRNA
2uxd, 2uxc - TtRPS10 in 30S ribosomal subunit+THX+A-site mRNA CGGG+tRNA anticodon+16S RRNA

1n32, 1n33 - TtRPS10 in 30S ribosomal subunit+THX+A-site mRNA fragment+tRNA anticodon+16S RRNA

1n34 - TtRPS10 in 30S ribosomal subunit+THX+A-site mRNA fragment +16S RRNA

1xmo, 1xmq - TtRPS10 in 30S ribosomal subunit+THX+A-site mRNA+tRNA anticodon+16S RRNA

2uxb - TtRPS10 in 30S ribosomal subunit+THX+A-site mRNA GGGU+tRNA anticodon+16S RRNA

S10 in small ribosomal subunit+P-site tRNA
3i8g - TtRPS10 in 30S ribosomal subunit+P-site tRNA+mRNA +16S RRNA

3i8h, 3i9b, 3i9d - TtRPS10 in 30S ribosomal subunit+THX+P-site tRNA+mRNA +16S RRNA

1ibk - TtRPS10 in 30S ribosomal subunit+THX+P-site mRNA fragment +16S RRNA

2wwl - EcRPS10 in 30S ribosomal subunit+Poly-Ala chain+P-site tRNA+mRNA +16S RRNA - Escherichia coli

3i1q - EcRPS10 in 30S ribosomal subunit+P-site tRNA hairpin+mRNA

3i1s, 3i1z, 3i21 - EcRPS10 in 30S ribosomal subunit+P-site tRNA hairpin+mRNA +16S RNA

S10 in small ribosomal subunit+A-site tRNA+P-site tRNA
1ibl, 1ibm - TtRPS10 in 30S ribosomal subunit+THX+A-site mRNA fragment+P-site mRNA fragment+tRNA anticodon+16S RRNAv

S10 in small ribosomal subunit+P-site tRNA+E-site tRNA
2ow8 - TtRPS10 in 30S ribosomal subunit+THX+P-site tRNA Phe+E-site tRNA+mRNA +16S RRNA

2b9o - TtRPS10 in 30S ribosomal subunit+THX+P-site tRNA Phe+E-site tRNA Phe+mRNA +16S RRNA

2qnh - TtRPS10 in 30S ribosomal subunit+THX+P-site tRNA+E-site tRNA+mRNA +16S RRNA

2wdg, 2wdh, 2wdk, 2wdm - TtRPS10 in 30S ribosomal subunit+THX+P-site tRNA+E-site tRNA+mRNA +16S RRNA+tRNA Phe

S10 in small ribosomal subunit+A-site tRNA+P-site tRNA+E-site tRNA
2gy9, 2gyb - EcRPS10 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+mRNA +16S RRNA – Cryo-EM

1jgo, 1jgp, 1jgq, 1gix - TtRPS10 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+tRNA Phe+mRNA +16S RRNA

3e1a, 3e1c - EcRPS10 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+mRNA +16S RRNA

S10 in small ribosomal subunit + antibiotics
1i95, 1i97,2hhh, 2f4v, 3oge, 3ogy, 3ohc, 3ohd, 3ohy, 3oi0, 3oi2, 3oi4 - TtRPS10 in 30S ribosomal subunit+16S RRNA+antibiotic

1hnw, 1hnx, 1hnz, 1fjg - TtRPS10 in 30S ribosomal subunit+16S RRNA+mRNA fragment+antibiotic

2qbb, 2qb9, 1vs5, 1vs7, 2qan, 2qal, 2qou, 2qow, 2qoy, 2qp0, 2z4k, 2z4m, 3oaq, 3oar, 3ofa, 3ofb, 3ofo, 3ofp, 3ofx, 3ofy - EcRPS10 in 30S ribosomal subunit+16S RRNA+antibiotic

2j00, 2j02 - TtRPS10 in 30S ribosomal subunit+16S RRNA+paromomycin+P-site tRNA fMet+E-site tRNA Phe+mRNA

3knj, 3knh - TtRPS10 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+mRNA +16S RRNA+viomycin

3knl, 3knn - TtRPS10 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+mRNA +16S RRNA+capreomycin

S10 in small ribosomal subunit + ribosome recycling factor
2qbd, 2qbf – EcRPS10 in 30S ribosomal subunit+16S RRNA+ribosome recycling factor

3r8n, 3r8o – EcRPS3 in 30S ribosomal subunit+16S RRNA+ribosome recycling factor + mRNA + tRNA

2qbh, 2qbj - EcRPS10 in 30S ribosomal subunit+16S RRNA+ribosome recycling factor+gentamicin

2v46, 2v48 - TtRPS10 in 30S ribosomal subunit+16S RRNA+ribosome recycling factor+P-site tRNA Phe+mRNA+tRNA fMet

S10 in small ribosomal subunit + elongation factor
2wri, 2wrk - TtRPS10 in 30S ribosomal subunit+THX+P-site tRNA+mRNA +16S RRNA+elongation factor G

2wrn, 2wrq - TtRPS10 in 30S ribosomal subunit+THX+A-site tRNA+mRNA +16S RRNA+elongation factor TU-4

3fic - TtRPS10 in 30S ribosomal subunit+THX+A-site tRNA+P-site tRNA+E-site tRNA+mRNA codon+16S RRNA+elongation factor TU-A

3izv – EcRPS10 in 30S ribosomal subunit+A/T-site tRNA Phe +16S RRNA+elongation factor TU

3izw – EcRPS10 in 30S ribosomal subunit+A-site tRNA Phe +mRNA +16S RRNA+elongation factor TU

2y0u, 2y0w, 2y0y, 2y10,  2y12, 2y14, 2y16,  2y18 - TtRPS10 in 30S subunit+THX+A-site tRNA+E-site tRNA+mRNA codon+16S RRNA+elongation factor TU

3fih - EcRPS10 in 30S ribosomal subunit+A-site tRNA Phe+P-site tRNA+mRNA +16S RRNA+elongation factor TU

3huw, 3huy - TtRPS10 in 30S ribosomal subunit+THX+tRNA-Met+mRNA +16S RRNA+elongation factor P

S10 in small ribosomal subunit + translation initiation factor
1i96 - TtRPS10 in 30S ribosomal subunit+THX+IF3+16S RRNA

1hr0 - TtRPS10 in 30S ribosomal subunit+THX+IF+16S RRNA

S10 in small ribosomal subunit + various proteins
3kiq, 3kis, 3kiu, 3kix - TtRPS10 in 30S ribosomal subunit+toxin RelE+16S RRNA

1voq, 1vos, 1vov, 1vox, 1voz - EcRPS10 in 30S ribosomal subunit+protein Y+16S RRNA

2xfz, 2xg1 - TtRPS10 in 30S ribosomal subunit+tRNA Phe+mRNA+colicin E3+16S RRNA

3j00 – EcRPS10 + 16S RRNA + FTSQ + apolipoprotein A-I

2xzm, 2xzn - RPS10 in 40S subunit+18S RRNA+RACK1 - Tetrahymena thermophila